Yes, you can use blur reduction at any supported resolution on the Z-series. With the BENQ Z-Series, you can use either monitor scaling (for certain resolutions) or GPU scaling (for most resolution). The Z-Series monitors can use external boxes such as gaming consoles, for 60Hz strobing.
Blur reduction only bothers some people. It depends on the person. Depending on the use case,
strobing actually can reduce eyestrain for some usage scenarios if you get more eyestrain from motion blur than from flicker. In fact, EIZO
advertises their commercial/mapping/military strobing monitor as reducing eyestrain. Also, the
LightBoost FAQ has both entries for "Why Does LightBoost Have MORE Eyestrain?"
AND "Why Does LightBoost Have LESS Eyestrain?". There are a lot of
testimonials where people love the blur reduction effect. As a rule of thumb, if you weren't bothered by CRT flicker or plasma flicker, then strobing flicker (especially at 100Hz+) will generally not bother you. In fact, there are also many here who like strobing even at lower strobe rates 60Hz. The bottom line is in all the strobed monitors, you can easily turn on/off the strobing feature, so the existence of the feature isn't a dealkiller. It's there for you to try out, and if not, the other features (e.g. 120Hz+, GSYNC, low blue light, etc) often make the purchase of the monitor worthwhile for a lot of "Better Than 60Hz" users.