So obviously the problem is with BIOS. Since after flashing BIOS all the settings reset to default it just could've disabled/enabled back some option that affects your mouse, or the r0ach's version. If i was you i would try to test every possible setting in BIOS on/off. Make sure your HPET is turned on in BIOS though.
Try to apply these settings in BIOS (copied from
Sweaty Gamer Club Optimization Guide):
These are very important to get right as they have a giant effect on system latency and PC performance. The guide covers settings related mostly to Intel CPUs, but you can find similar options for AMD ones too. Names for options may differ by motherboard brand/edition. Settings in the BIOS are usually organized by category, but may be all over the place - therefore it's useful to check every submenu.
Disable the integrated GPU - you will be using a PCIE one.
Disable integrated audio if you have a soundcard.
Disable all E-Cores - they add latency/microstutter, as well as inferior performance for most games (you can’t OC P-Cores as high). This can be done by setting the amount of E-Cores to 0.
P-Cores should be at maximum (enable all).
Disable Hyperthreading.
Set CPU Ratio Mode to “fixed” - and apply a static clock speed to the max stable MHz your temps can handle by setting the core multiplier.
Set the SA/Ring/Cache multiplier to max stable.
Disable Intel Adaptive Thermal Monitor / CPU Over Temperature Protection.
Disable Intel C-State support. Disable all displayed C-States such as C1E. We don’t want ANY power saving on our CPU.
Disable Intel Speed Shift / Intel Speed Step.
BCLK lock-on should be at 100mhz.
If your RAM supports a XMP overclock, set it to the max it can. Overclocked RAM results in better FPS and especially lows.
Disable Intel Virtualization / VT-D.
Enable Resizable Bar for your GPU.
Disable secure boot.
For more in depth BIOS modding, see Hidden Bios Settings, which explains how to use GRUB/SCEWIN to fully optimize it.
As r0ach said try to reverse to the exact same BIOS version you had, if not possible, you can try going to some PC service center, i believe there is some more advanced way of changing BIOS version. If again no luck - buy new motherboard lol
I would also advise to read this guide from Calypto